Friday, November 30, 2012

Mountain Biking, an Excellent form of Recreation and Sports ...

7 hours ago

For most, mtn biking is a recreational sports activity wherein riders ride bicycles off-road on tough terrains. The bicycles used for these activity is specifically manufactured to suit these kind of terrains which are generally rough and patchy. Such bikes are preferredly known as mntain bikes. These mountain bikes are especifically suitable for these kinds of environments. These forms of bikes look very similar to any other bike, but they are fitted with special features to increase and improve the ride, comfort and most importantly performance on such terrains.

Terrain biking are of different categories such as hybrid country, dirt jumping and trails to name a few. The most well-liked forms of mountain biking is the recreational and trail driving categories. One can perform mtn biking anywhere like on country back roads, off-road trails, zigzag roads thtough forests, on hills or mountains, flds and on roads. since mountain biking involves journeyling on your own and most of the time being away from the civilization, the rider needs to be self-reliant in the game. The rider is necessary to carry a backpack and be equipped with essential items like water, equipment needed for repairs, a first aid kit, and some emergency food packets in case of need arising from any unfortunate incident like accidents. mtn biking thtough clubs or in groups is very common on long treks. This hobby has gained in well-likedity after the year 1990 and is recognized as a form of recreational sports activity.

Some of the equipments one needs for mountain biking are, a good bike specifically made for performance on terrains which are rough. They have particular exclusive features like dual suspension, broader tires, and flat and raised take care of for comfortable riding posture giving good control for the rider. These make of bikes come fitted with disc brakes and gears to assist in climbing hills which are steep and travel thtough bumpy surfaces. Due to these unique capabilities such bikes are heavier as compared to the regular tour bicycles. A rider also needs to carry sure accessories like helmets, gloves, first aid kit, GPS device, pumps to fill flat tires, a good shoe, instruments for the bike etc.

cross country is the most preferred form of off-road biking all over the world. This involves travelling from one point to another involving some climbs and descents on different forms of terrains. Trails involve jumping the bikes over obstacles without the rider?s foot touching the land. It is generally performed off-road and requires good balance from the rider. each and every game has its risks and mntain biking also involves some risks. Without the use of any protective gears a rider can be inclined to Minimal as well as some severe injuries to head or spine especifically in downhill biking. With a protective gear one can avoid such critical injuries.

Australia has some excellent terrain biking tours which are eco certified, these tours come with instructions for every single kind of biking practical experience be it the rainforest tours or the coastal tours on bikes. They cater to all kinds of rider amateur as well as experienced. expertise the adventures involved in mountain biking like any other game and also enjoy dynamics at its best. Such form of biking is a great stress buster.


Source: http://en.netlog.com/emoryeckis/blog/blogid=14603313

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Source: http://lovellchristie.typepad.com/blog/2012/11/mountain-biking-an-excellent-form-of-recreation-and-sports.html

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Source: http://ripedygan.wordpress.com/2012/11/30/mountain-biking-an-excellent-form-of-recreation-and-sports/

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Thursday, November 29, 2012

AP Exclusive: Disney, Sears used factory in fire

Bangladeshi garments workers take out a protest through the streets to mourn the death of the victims of Saturday's fire in a garment factory on the outskirts of Dhaka, Bangladesh, Tuesday, Nov. 27, 2012. Bangladesh held a day of mourning Tuesday for the 112 people killed in a weekend fire at a garment factory, and labor groups planned more protests to demand better worker safety in an industry notorious for operating in firetraps. (AP Photo/Ashraful Alam Tito)

Bangladeshi garments workers take out a protest through the streets to mourn the death of the victims of Saturday's fire in a garment factory on the outskirts of Dhaka, Bangladesh, Tuesday, Nov. 27, 2012. Bangladesh held a day of mourning Tuesday for the 112 people killed in a weekend fire at a garment factory, and labor groups planned more protests to demand better worker safety in an industry notorious for operating in firetraps. (AP Photo/Ashraful Alam Tito)

Bangladeshi women watch the bodies of some of the victims of Saturday's fire in a garment factory being prepared to be buried, in Dhaka, Bangladesh, Tuesday, Nov. 27, 2012. Bangladesh held a day of mourning Tuesday for the 112 people killed at the factory, and labor groups planned more protests to demand better worker safety in an industry notorious for operating in firetraps. (AP Photo/Khurshed Rinku)

Bangladeshis prepare to bury the bodies of some of the victims of Saturday's fire in a garment factory in Dhaka, Bangladesh, Tuesday, Nov. 27, 2012. Bangladesh held a day of mourning Tuesday for the 112 people killed at the garment factory, and labor groups planned more protests to demand better worker safety in an industry notorious for operating in firetraps. (AP Photo/Rehman Asad)

Bangladeshis prepare to bury the bodies of a part of the victims of Saturday's fire in a garment factory in Dhaka, Bangladesh, Tuesday, Nov. 27, 2012. Bangladesh held a day of mourning Tuesday for the 112 people killed in a weekend fire at a garment factory, and labor groups planned more protests to demand better worker safety in an industry notorious for operating in firetraps. (AP Photo/Pavel Rahman)

DHAKA, Bangladesh (AP) ? Amid the ash, broken glass and melted sewing machines at what is left of the Tazreen Fashions Ltd. factory, there are piles of blue, red and off-white children's shorts bearing Wal-Mart's Faded Glory brand. Shorts from hip-hop star Sean Combs' ENYCE label lay on the floor and are stacked in cartons.

An Associated Press reporter searching the factory Wednesday found these and other clothes, including sweaters from the French company Teddy Smith, among the equipment charred in the fire that killed 112 workers Saturday. He also found entries in account books indicating that the factory took orders to produce clothes for Disney, Sears and other Western brands.

Garments and documents left behind in the factory show it was used by a host of major American and European retailers, though at least one of them ? Wal-Mart ? had been aware of safety problems. Wal-Mart blames a supplier for using Tazreen Fashions without its knowledge.

The fire has elevated awareness of something labor groups, retailers and governments have known for years: Bangladesh's fast-growing garment industry ? second only to China's in exports ? is rife with dangerous workplaces. More than 300 workers there have died in fires since 2006.

Police on Wednesday arrested three factory officials suspected of locking in the workers who died in Saturday's fire, the deadliest in the South Asian country's less than 35-year history of exporting clothing.

Local police chief Habibur Rahman said the three will be questioned amid reports that many workers trying to escape the blaze had been locked inside. He said the owner of the factory was not among those arrested.

The three officials were arrested Wednesday at their homes in Savar, the Dhaka suburb where the factory is also located. Rahman did not identify the officials or give their job status.

About 1,400 workers worked at the plant, some 70 percent of them women. Most are from the north, the poorest region of Bangladesh.

Workers who survived the fire say exit doors were locked, and a fire official has said that far fewer people would have died if there had been even one emergency exit. Of the dead, 53 bodies were burned so badly they could not be identified; they were buried anonymously.

The fire started on the ground floor, where a factory worker named Nasima said stacks of yarn and clothes blocked part of the stairway.

Nasima, who uses only one name, and other workers said that when they tried to flee, managers told them to go back to their work stations, but they were ignored.

Dense smoke filled the stairway, making it hard to see, and when the lights went out the workers were left in total darkness. Another worker, Mohammad Rajib, said some people used their cellphones to light their way.

"Everyone was screaming for help," Nasima said. "Total chaos, panic and screaming. Everyone was trying to escape and come out. I was pulling the shirt of a man. I fainted and when I woke up I found myself lying on the road outside the factory.

"I don't know how I survived."

Rajib said the factory conducted a fire drill just three days before the fire broke out, but no one used the fire extinguishers. "Only a selected group of workers are trained to use the extinguishers. Others have no idea how to use them," he said.

The AP reporter who examined the factory Wednesday saw dozens of fire extinguishers with tags indicating they were inspected early this month. Many appeared unused.

Workers expressed support for the factory owner, Delwar Hossain. Rajib said he is "a gentle man" who heeded workers when they protested for more pay and against rough behavior by some managers.

"He took action and fired some of them," he said. "He did not sack any worker. He told us: 'You are my people. If you survive, I will survive.'"

Most the fire's devastation took place on the second and third floors. Sewing and embroidery machines and tables burned to ashes, ceiling fans melted and floor and wall tiles were broken, apparently because of excessive heat. Thick black ash covers everything in the upper floors of the eight-story building.

Much of the clothing on the lower floors was incinerated. Nightgowns, children's shorts, pants, jackets and sweat shirts were strewn about, piled up in some places, boxed in others. Cartons of kids' hooded sweaters, off-white with red and black print, were marked "Disney Pixar."

There were also at least four register books listing buyers including Wal-Mart, Disney, Sears and other companies. Also listed was Li & Fung, a Hong Kong-based buying house that is among the biggest suppliers of garment products from Bangladesh. Li & Fung issued a statement Monday saying it placed orders at the factory for just one company, Kids Headquarters, and that the value of those orders totaled just $111,000.

Prime Minister Sheikh Hasina and Interior Minister Muhiuddin Khan Alamgir have said arson is suspected. Police say they have not ruled out sabotage.

Wal-Mart had received an audit deeming the factory "high risk" last year, said it had decided to stop doing business with Tazreen, but that a supplier subcontracted work to the factory anyway. Wal-Mart said it stopped working with that supplier on Monday.

Calls made to The Walt Disney Company and to Sears Holdings were not immediately returned.

Local TV reports said about 3,000 garment workers held protests over the fire Wednesday, blocking roads and throwing stones at some factories and vehicles. It was the third straight day of demonstrations, and as they did previously, factories in the area closed to avoid violence.

Police used batons to disperse the protesters, but no injuries were immediately reported.

According to local television, most factories in the area closed after opening briefly because of the protests ? a common tactic to avoid violence.

___

Associated Press writer Farid Hossain in Dhaka, Bangladesh, contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2012-11-28-Bangladesh-Factory%20Fire/id-25c132f5f4c44dbeb367cae5c65fcebc

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12/02/2012 - Samuel Merritt University Nursing Pinning Ceremony

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Source: http://www.collegeofsanmateo.edu/calendar/events/index.php?com=detail&eID=9020

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Wednesday, November 28, 2012

Study points to potential new therapies for cancer and other diseases

Wednesday, November 28, 2012

Researchers at The Scripps Research Institute (TRSI) are fueling the future of cancer treatment by improving a powerful tool in disease defense: the body's immune system. By revealing a novel but widespread cell signaling process, the scientists may have found a way to manipulate an important component of the immune system into more effectively fighting disease.

The study, recently published online ahead of print by the journal Blood, shows that disabling a particular enzyme, called ItpkB, in mice improves the function of a type of immune cell called Natural Killer cells.

"This is an exciting finding because it could possibly lead to the development of drugs that improve Natural Killer cell function," said TSRI Associate Professor Karsten Sauer, PhD, who led the study. "Natural Killer cells have gained clinical interest as innovative biological therapeutics for certain cancers and also in certain infectious diseases."

The Body's 'SWAT Team'

Natural Killer cells patrol the body and detect characteristic alterations on the surface of cancer cells or virus-infected cells. Through a complicated and little understood signaling machinery?a domino effect of molecular reactions in a cell that ultimately produces a certain signal?Natural Killer cells then destroy such "stressed" cells.

Compared to other types of immune cells, Natural Killer cells kill these cells quickly. This makes Natural Killer cells important early responders of the immune system. Not surprisingly, researchers have explored engaging this "SWAT team" of the body therapeutically, particularly in blood cancers.

However, to date, the therapeutic efficacy of Natural Killer cells has been limited. "A key bottleneck is our limited understanding of signaling mechanisms that dampen Natural Killer cell function," Sauer said.

Sauer and colleagues' new research reveals crucial details of this puzzle.

A Way to Prime the Attack

The Sauer group had previously identified ItpkB as a key regulator of immune function. ItpkB acts primarily by producing IP4, a small molecule messenger that controls the functions of various other important signaling molecules. IP4 can improve or inhibit signaling depending on the cell type in which it is produced.

The new research showed that Natural Killer cells from mice lacking ItpkB show elevated signaling and function better than Natural Killer cells that have the enzyme. As a result, mice lacking ItpkB are more effective than mice expressing ItpkB in attacking cells that display characteristic surface changes of cancer cells.

"The enzyme ItpkB has unique features that facilitate its highly specific inhibition by small molecules," said Sauer. "Our findings suggest that such compounds could possibly be used to improve Natural Killer cell function therapeutically. If successful, this could overcome a bottleneck and engage the body's SWAT team to fight cancer."

###

Scripps Research Institute: http://www.scripps.edu

Thanks to Scripps Research Institute for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/125545/Study_points_to_potential_new_therapies_for_cancer_and_other_diseases

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Shocker Alert: New York Times Writer Pines for ?Progressive? 19th ...

The New York Times had a real doozey of an op-ed today ? one longing for the good ole days of publicly funded canals, highways and airports, and urging heavy-handed government monopoly regulation of our communications networks to ?improve? our supposedly crummy, cartelized communications marketplace.

It?s an instant New York Times classic. ?You?ve got network providers equated to drug dealers. ?We read how, through the supposed failure of the greedy U.S. broadband ?cartel,? France and other under-developed countries are easily surpassing our (don?t say exceptional) country in broadband services and speeds. ?We see the gratuitous connection of the ?cartel? to the work of its ugly lobbyists.

In short, you?ve got all the progressive dog-whistle stuff that makes the New York Times so ?great? for its readers.

And yet so atrociously wrong.

Let?s get real here.? Since 1996 ? when government monopolies of communications networks were essentially outlawed by Congress ? the growth of our broadband networks represents a truly remarkable American success story.? Over the past 15 years, industry figures show that more than $1 trillion of private investment ? or about $73 billion per year ? has flooded onto America?s broadband communications landscape.? Consequently, in any given market, instead of finding just plain old telephone service (POTS), broadband access is universal.? In fact, 99% of Americans can access at least one flavor of facilities-based broadband ? be it DSL, cable modem, fiber, cable-fiber hybrids, satellite, broadband over powerline or wireless services ? through any one of the 1,556 broadband providers across the U.S.

But wait, there?s more.? U.S. broadband infrastructure didn?t just change and become more innovative for itself, it helped forge whole new markets, too ? such as the smartphone, the tablet, the cloud, Facebook, YouTube, Pandora, etc. ? enabling an $8 trillion exchange of goods and services each year.

It?s also made the American worker among the most productive and competitive in the world, and which, according to some government-cited estimates, has propelled 15% of our GDP growth since 2004.

Could this Internet ecosystem success story have occurred in a heavily regulated, 19th?Century model as advocated by the author?

No.

As FCC Chairman, Julius Genachowski, noted last year, ?Over the past 15 years, the Internet has enabled as much economic growth as the Industrial Revolution generated in its first 50 years.?? Not coincidentally, this explosion occurred in an environment marked by deregulation ? one which plainly, clearly, forever (one hopes) jettisoned 19th Century monopoly communications regulation. ?Stated differently, that growth did not happen by virtue of heavily regulated POTS.

The progressive lament that the marketplace stinks is perennial as the change of seasons.? In their view, only through cartels of policymakers, wielding coercive regulations, can network providers be made to be ?truly competitive.?

Gee.? That worked, didn?t it?

Not.

FDR-era laws, which codified 19th Century regulation, is no way to serve the public interest in the 21st Century.? Rather, as we?ve seen over the past 15 years, the advance of technology, consumer education tools, industry best practices, and marketplace guidance is far better suited to meeting the evolving needs of consumers than any ?well meaning? law seemingly pined for by the author.

The market will continue to grow and improve, and consumers will continue to enjoy tremendous value and benefit from the Internet ecosystem, as long as we can avoid going back to the ?progressive? 19th Century.

?

Source: http://mediafreedom.org/2012/11/shocker-alert-new-york-times-writer-pines-for-progressive-19th-century-communications-regulation/

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Spotlight on Business - Holmes Security Systems | Pleasure Island ...


Holmes Security Systems is part of a 104 year old, family owned company, founded in Fayetteville, NC in 1908. We have offices in both Fayetteville and Wilmington, NC. Here?s how we run our?business:

We are a security company, not just an alarm company. We don?t run $99 specials or offer ?one size fits all? systems. Instead, we work with our customers to determine how best to protect their home, families, and businesses, realizing that an alarm system is only part of the solution.

We are a life safety company ? we look at all aspects of keeping your home, family and business safe. We don?t shy away from recommending monitored smoke and carbon monoxide detectors, and personal panic and medical alert devices.

We don?t have long term contracts ? we won?t ask you to sign a three or five year agreement. Our philosophy is that we want you to do business with us because you want to do business with us.
We are an Authorized Preferred Honeywell Dealer, with the additional First Alert Professional title in Wilmington. Honeywell is the world-wide leader in security solutions.

And finally, an effective security system must be monitored. We own and operate our own state-of-the-art, UL Listed Central Monitoring Station right here in southeastern NC. It?s staffed by trained personnel 24-7, and has achieved the 5 Diamond Certification from the Central Station Alarm Association (CSAA). In fact, it is the only such center in Eastern NC. Local monitoring means faster response.

We are A+ rated by the Better Business Bureau, and we offer all of the benefits of a national company, but the money stays in our community. Local ownership, local service, local monitoring, and no long term contracts, plus a definite price advantage.

Call us at 793-4181 or find us on the web at www.HolmesSecurity.net.

Source: http://pleasureislandchamber.blogspot.com/2012/11/spotlight-on-business-holmes-security.html

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